Neal Jr. Castagnoli : rechercher sur Z-Library

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1

Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke

Ashraf A. Khalil, Bruce Davies, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 155 KB

english, 2006

2

Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B

Anél Pretorius, Modupe O. Ogunrombi, Hendrik Fourie, Gisella Terre’Blanche, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 491 KB

english, 2010

3

Inhibition of Monoamine Oxidase Contributes to the Protective Effect of 7-Nitroindazole Against MPTP Neurotoxicity

Donato A. Di Monte, Joyce E. Royland, Andrea Anderson, Kay Castagnoli, Neal Castagnoli Jr., J. William Langston

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 314 KB

english, 1997

4

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

Kan Chiba, Anthony Trevor, Neal Castagnoli Jr.

Journal:

Biochemical and Biophysical Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 330 KB

english, 1984

5

Regioselective synthesis of deuterated analogs of the neurotoxin MPTP

Stéphane Mabic, Neal Castagnoli Jr.

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1996

Langue:

english

Fichier:

PDF, 312 KB

english, 1996

6

Regioselective deuterium labeling of 1,4-disubstituted-1,2,3,6-tetrahydropyridines

Stéphane Mabic, John M. Rimoldi, Neal Castagnoli Jr.

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1997

Fichier:

PDF, 643 KB

1997

7

Unexpected adduct ion formation under chemical ionization conditions

Donald G. Musson, Magnus M. Halldin, Deiji Karashima, Neal Castagnoli Jr.

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1986

Langue:

english

Fichier:

PDF, 559 KB

english, 1986

8

ChemInform Abstract: Studies on Synthetic Approaches to 1H- and 2H-Indazolyl Derivatives

Emre M. Isin, Milly de Jonge, Neal Castagnoli Jr.

Journal:

Année:

2001

Fichier:

PDF, 24 KB

2001

9

Rational Approaches Towards Reversible Inhibition of Type B Monoamine Oxidase. Design and Evaluation of a Novel 5H-Indeno[1,2-c]pyridazin-5-one Derivative.

Frederic Ooms, Raphael Frederick, Francois Durant, Jacobus P. Petzer, Neal Jr. Castagnoli, Cornelis J. Van der Schyf, Johan Wouters

Journal:

Année:

2003

Fichier:

PDF, 13 KB

2003

10

(E)-8-(3-Chlorostyryl)-1,3-7-trimethylxanthine, a Caffeine Derivative Acting Both as Antagonist of Adenosine A2A Receptors and as Inhibitor of MAO-B.

Raphael Frederick, Frederic Ooms, Neal Jr. Castagnoli, Jacques P. Petzer, Jiang-Fan Feng, Michael A. Schwarzschild, Cornelis J. Van der Schyf, Johan Wouters

Journal:

Année:

2006

Fichier:

PDF, 10 KB

2006

11

The synthesis of deuterium enriched erythro-α-methylnorepinephrine and norepinephrine

Asher Kalir, Curt Freed, Kenneth L. Melmon, Neal Castagnoli Jr.

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1977

Langue:

english

Fichier:

PDF, 746 KB

english, 1977

12

The syntheses of deuterium labelled tobacco alkaloids: Nicotine, nornicotine and cotinine

Trong-Lang Nguyen, Neal Castagnoli Jr

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1978

Langue:

english

Fichier:

PDF, 501 KB

english, 1978

13

Synthesis of specifically labeled (S)-nicotine-5-3H and (S)-cotinine-5-3H BY carrier free tritiolysis of the corresponding 5-bromo derivatives

Mark K. Shigenaga, Peyton Jacob, Anthony Trevor, Neal Castagnoli Jr., Neal Benowitz

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1987

Langue:

english

Fichier:

PDF, 499 KB

english, 1987

14

The synthesis of 13C-enriched α-methyldopa

Matthew M. Ames, Neal Castagnoli Jr.

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1974

Langue:

english

Fichier:

PDF, 393 KB

english, 1974

15

Mass spectrometric studies on 4-aryl-1-cyclopropyl-1,2-dihydropyridinyl derivatives: an examination of a novel fragmentation pathway

Philippe Bissel, Skye Geherin, Kazuo Igarashi, Richard D. Gandour, Iulia M. Lazar, Neal Castagnoli Jr

Journal:

Journal of Mass Spectrometry

Année:

2006

Langue:

english

Fichier:

PDF, 596 KB

english, 2006

16

The synthesis of pyrrolidine-substituted nicotine analogs

Neal Castagnoli Jr., Armen P. Melikian, Vittorio Rosnati

Journal:

Journal of Pharmaceutical Sciences

Année:

1969

Langue:

english

Fichier:

PDF, 478 KB

english, 1969

17

Synthesis of N-pentafluorobenzoyl-s-(−)-prolyl 1-imidazolide, a new electron-capture sensitive reagent for determination of enantiomeric composition

Shaikh B. Matin, Malcolm Rowland, Neal Castagnoli Jr.

Journal:

Journal of Pharmaceutical Sciences

Année:

1973

Langue:

english

Fichier:

PDF, 293 KB

english, 1973

18

Differing antitumor activities of the hydrochloride and methiodide salts of 1-ethyl-3-(3′-dimethylaminopropyl)- carbodiimide

Tom S. Tenforde, Rashid A. Fawwaz, Neal Castagnoli Jr.

Journal:

Journal of Pharmaceutical Sciences

Année:

1976

Langue:

english

Fichier:

PDF, 249 KB

english, 1976

19

Derivatization of chiral amines with (S,S)-N-Trifluoroacetylproline anhydride for GC estimation of enantiomeric composition

James D. Adams Jr., Anthony J. Trevor, Thomas F. Woolf, Lyall R. Williams, Neal Castagnoli Jr.

Journal:

Journal of Pharmaceutical Sciences

Année:

1982

Langue:

english

Fichier:

PDF, 555 KB

english, 1982

20

The metabolism of tertiary amines

Janine Rose, Neal Castagnoli Jr.

Journal:

Medicinal Research Reviews

Année:

1983

Langue:

english

Fichier:

PDF, 800 KB

english, 1983

21

Selective inhibitors of monoamine oxidase (MAO-A and MAO-B) as probes of its catalytic site and mechanism

Amit S. Kalgutkar, Neal Castagnoli Jr., Bernard Testa

Journal:

Medicinal Research Reviews

Année:

1995

Langue:

english

Fichier:

PDF, 3.38 MB

english, 1995

22

Decyclopropylation of 1-cyclopropyl-4-hydroxy-4-(2-methylphenyl)piperidine N-oxide

You-Xiong Wang, Neal Castagnoli Jr.

Journal:

Tetrahedron Letters

Année:

1995

Langue:

english

Fichier:

PDF, 174 KB

english, 1995

23

Cyclic voltammetry with cyclic iminium ions: Implications for charge transfer with biomolecules (metabolites of nicotine, phencyclidine, and spermine)

James R. Ames, Svante Brandänge, Benito Rodriguez, Neal Castagnoli Jr., Michael D. Ryan, Peter Kovacic

Journal:

Bioorganic Chemistry

Année:

1986

Langue:

english

Fichier:

PDF, 817 KB

english, 1986

24

Determination of the pyridinium metabolite derived from haloperidol in brain tissue, plasma and urine by high-performance liquid chromatography with fluorescence detection

Kazuo Igarashi, Neal Castagnoli Jr.

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1992

Langue:

english

Fichier:

PDF, 592 KB

english, 1992

25

Studies on the cytochrome P450 catalyzed oxidation of 13C labeled 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine by 13C NMR

Philippe Bissel, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 218 KB

english, 2005

26

Corrigendum to “Studies on the cytochrome P450 catalyzed oxidation of 13C labeled 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine by 13C NMR”: [Bioorg. Med. Chem. 13 (2005) 2975]

Philippe Bissel, Neal Castagnoli Jr., Sarah Penich

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Fichier:

PDF, 65 KB

2005

27

Corrigendum to “Studies on the cytochrome P450 catalyzed oxidation of 13C labeled 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine by 13C NMR” [Bioorg. Med. Chem. 13 (2005) 2975]

Philippe Bissel, Neal Castagnoli Jr., Sarah Penich

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Fichier:

PDF, 47 KB

2005

28

A novel and selective monoamine oxidase B substrate

John M. Rimoldi, Satish G. Puppali, Emre Isin, Philippe Bissel, Ashraf Khalil, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 270 KB

english, 2005

29

Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC)

Nevil Vlok, Sarel F. Malan, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 207 KB

english, 2006

30

Synthesis and in vitro biological evaluation of fluoro-substituted-4-phenyl-1,2,3,6-tetrahydropyridines as monoamine oxidase B substrates

Aaron B Beeler, Rama Sarma V.S Gadepalli, Salome Steyn, Neal Castagnoli Jr, John M Rimoldi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 196 KB

english, 2003

31

Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues

Deidré van den Berg, Kevin R. Zoellner, Modupe O. Ogunrombi, Sarel F. Malan, Gisella Terre’Blanche, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 243 KB

english, 2007

32

Structure–activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles

Modupe O. Ogunrombi, Sarel F. Malan, Gisella Terre’Blanche, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 750 KB

english, 2008

33

Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane

Philippe Bissel, Ashraf Khalil, John M. Rimoldi, Kazuo Igarashi, Dale Edmondson, Anthony Miller, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 237 KB

english, 2008

34

Dual inhibition of monoamine oxidase B and antagonism of the adenosine A2A receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues

Judey Pretorius, Sarel F. Malan, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 261 KB

english, 2008

35

The tert-butoxyl radical mediated hydrogen atom transfer reactions of the Parkinsonian proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and selected tertiary amines

N. Kamrudin Suleman, Joey Flores, James M. Tanko, Emre Mehmet Isin, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 292 KB

english, 2008

36

Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B

Anél Pretorius, Modupe O. Ogunrombi, Gisella Terre’Blanche, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 355 KB

english, 2008

37

Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides

Clarina I. Manley-King, Gisella Terre’Blanche, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 560 KB

english, 2009

38

Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues

Belinda Strydom, Sarel F. Malan, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2010

39

Inhibition of monoamine oxidase by (E)-styrylisatin analogues

Elizna M. Van der Walt, Erika M. Milczek, Sarel F. Malan, Dale E. Edmondson, Neal Castagnoli Jr., Jacobus J. Bergh, Jacobus P. Petzer

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 559 KB

english, 2009

40

Synthesis and Biological Evaluation of MAO-A Selective 1,4-Disubstituted-1,2,3,6-tetrahydropyridinyl Substrates

Philippe Bissel, Mark C Bigley, Kay Castagnoli, Neal Castagnoli Jr

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 230 KB

english, 2002

41

Chemical model studies on the monoamine oxidase-B catalyzed oxidation of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridines

Christelle Franot, Stéphane Mabic, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 971 KB

english, 1997

42

1-Methyl-3-pyrrolines and 2-methylisoindolines: new classes of cyclic tertiary amine monoamine oxidase B substrates

You-Xiong Wang, Stéphane Mabic, Neal Castagnoli Jr

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 212 KB

english, 1998

43

Synthesis and MAO-B Substrate Properties of 1-Methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines

Jian Yu, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 236 KB

english, 1999

44

Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine

Zhiyang Zhao, Stéphane Mabic, Simon Kuttab, Christelle Franot, Kay Castagnoli, Neal Castagnoli Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 887 KB

english, 1998

45

Electron ionization-induced loss of a methyl radical from 1-cyclopropyl-4-substituted-1,2,3,6 tetrahydropyridine derivatives

Stéphane Mabic, Sandeep K. Nimkar, Dana N. Harris, Kim Harich, Neal Castagnoli Jr.

Journal:

Journal of the American Society for Mass Spectrometry

Année:

1997

Langue:

english

Fichier:

PDF, 318 KB

english, 1997

46

Naphthoquinones and bioactive compounds from tobacco as modulators of neuronal nitric oxide synthase activity

Priya Venkatakrishnan, C. Gary Gairola, Neal Castagnoli Jr, R. Timothy Miller

Journal:

Phytotherapy Research

Année:

2009

Langue:

english

Fichier:

PDF, 211 KB

english, 2009

47

Study of the electrospray ionization mass spectrometry of the proton pump inhibiting drug Omeprazole

Lars Weidolf, Neal Castagnoli Jr

Journal:

Rapid Communications in Mass Spectrometry

Année:

2001

Langue:

english

Fichier:

PDF, 270 KB

english, 2001

48

P450-catalyzed vs. electrochemical oxidation of haloperidol studied by ultra-performance liquid chromatography/electrospray ionization mass spectrometry

Tove Johansson Mali'n, Lars Weidolf, Neal Castagnoli Jr., Ulrik Jurva

Journal:

Rapid Communications in Mass Spectrometry

Année:

2010

Langue:

english

Fichier:

PDF, 169 KB

english, 2010

49

Reaction of benzophenone triplet with aliphatic amines. What a potent neurotoxin can tell us about the reaction mechanism

Michelle L. Grimm, William J. Allen, Meghan Finn, Neal Castagnoli Jr., James M. Tanko

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 820 KB

english, 2011

50

Dual-target-directed drugs that block monoamine oxidase B and adenosine A2Areceptors for Parkinson’s disease

Jacobus P. Petzer, Neal Castagnoli Jr, Michael A. Schwarzschild, Jiang-Fan Chen, Cornelis J. Van der Schyf

Journal:

Neurotherapeutics

Année:

2009

Langue:

english

Fichier:

PDF, 221 KB

english, 2009